Mesothelioma Prognosis and Prolonged Life Expectancy

Writer : Dr. Naskan

Estimated Lifespan of Mesothelioma. A mesothelioma patient's life expectancy ranges from 12 to 21 months following diagnosis. Based on their tumor location and type as well as their stage of cancer and mesothelioma, some patients with the disease may live longer and healthier lives.

How Long Will I Live With Mesothelioma?

Patients with mesothelioma have a one-year survival rate. It depends on a variety of factors, including the type of mesothelioma that a person has. The most important factor, however, is the stage of cancer in the patient. Depending on the size and spread of the tumor, doctors can use stages to determine the most effective treatment and assess the prognosis of their patients.

The prognosis of a patient is described by doctors using terms like "life expectancy," "life span," and "survival rate." Despite their similarity, these terms are not interchangeable. Understanding what they mean for your prognosis is helpful.

  • A person's prognosis provides an overview of the likely effects of mesothelioma on their health.
  • Mesothelioma patients' life expectancies and lifespans are measured in terms of how long they are expected to live.
  • The percentage of patients who are still alive five years after diagnosis is known as the survival rate. It is also possible to take the test one and two years after the diagnosis has been completed. Mesothelioma patients have a 15-month median survival time.
  • Different survival rates are meant by the terms "average" and "median." Total survival time is divided by the number of patients in a study to arrive at an average. The median is the midpoint between the two extremes of survival time.

Different Mesothelioma Types Have Different Lifespans

Depending on the type of mesothelioma, the average life expectancy ranges from six months to five or more years. What distinguishes the various types of mesothelioma is where they originate in the human body. Life expectancy is significantly reduced due to the fact that mesothelioma affects a number of vital organs, including the heart.

How Long Do People Live With Pleural Mesothelioma?

Pleural mesothelioma is a cancer that develops in the lining of the lungs and can be surgically removed in some patients, extending their lives by an average of three years.

Nearly 75% of mesothelioma patients who are diagnosed with lung cancer survive for at least a year.

Life expectancy after peritoneal mesothelioma

As many as half the patients with aggressive peritoneal cancer treatment can expect to live for five or more years after diagnosis.

In comparison to pleural mesothelioma, stomach mesothelioma is easier to surgically remove. In patients with peritoneal mesothelioma, surgery has a greater impact on life expectancy than in those with pleural disease.

Survivorship Rates for Mesothelioma of the Pericardium and Testicles

Pericardial mesothelioma is an extremely rare subtype. About one percent of patients have this variation, which develops around the heart's protective membranes. Six to 10 months is the average survival time for pericardial mesothelioma.

Approximately 5 percent of mesothelioma patients are diagnosed with testicular cancer. Two years is the average lifespan for testicular mesothelioma patients.

Mesothelioma's Life Expectancy Factors

Mesothelioma patients' life expectancies are influenced by a number of variables, including the stage of the disease and their age at diagnosis. Mesothelioma treatments, clinical trials, and better health and lifestyle choices are all things that can be managed.


  • Oncology terms, stage refers to how far along a patient's cancer has progressed.
  • It is important to know the exact location of the tumor in order to determine the type of mesothelioma it is.
  • Sarcomatoid and epithelial cell types differ in their response to treatment.
  • Patients who are younger when they are diagnosed with mesothelioma have a better prognosis.
  • Diagnoses and survival rates differ between men and women because of their gender.
  • Health and Lifestyle: Poor health and habits can affect the life expectancy of mesothelioma patients.
  • Survival may be affected by a patient's response to treatment, such as surgery or chemotherapy.
  • Cancer patients who participate in clinical trials are more likely to live longer.

As part of your prognosis, which is the overall outlook on how mesothelioma will affect your body and life span, your life expectancy is critical.

Mesothelioma Stage

The most significant determinant of prognosis for mesothelioma patients is the stage of the cancer at the time of diagnosis. Staging is a medical term used to describe how far cancer has progressed at the time of a patient's diagnosis.

A cancer's stage can range from 1-4. Prognosis gets worse as stage number increases, and life expectancy gets shorter. Because the cancer has spread to vital organs, the prognosis has worsened.

Type of Cancer Cell: Mesothelioma Cells

It has been found that patients with epithelioid cell type (also known as epithelial tumor) have a median survival time of 200 days longer than those with biphase or sarcomatous disease. This is due to the fact that treatments work better on epithelial cells.

For Sarcomatoid MeSO, treatment is less effective and the disease is oftentimes recurrence-resistant.


Patients with mesothelioma who are younger have a better prognosis. More treatment options and clinical trials are available to younger mesothelioma patients because they are more likely to be in good health. Because of these differences, people with mesothelioma who are diagnosed earlier in life have a longer life expectancy.

4,526 newly diagnosed nonmetastatic malignant pleural mesothelioma patients aged 80 and over were studied in a National Cancer Database study in 2019. In the study, only 2% of the patients received surgery and chemotherapy, while 63% of the patients received no therapy. The observed (no treatment) group had a median survival of 4.1 months.

The surgery and chemotherapy group had a median survival of 12.2 months. On average, patients who only received chemotherapy lasted 9.5 months. 28.5 percent of the 8 percent of patients who underwent surgery died within 90 days of their procedure.

Surgical intervention can extend the lives of elderly mesothelioma patients, but it comes with a high level of risk.


For every one man diagnosed with mesothelioma, there are four women. Women with epithelial mesothelioma also live longer on average than men with the same cell type.

Asbestos exposure, the primary cause of mesothelioma, is typically less intense in women, who tend to live longer. There is a possibility that less aggressive tumors could result.

The type of mesothelioma is yet another contributing factor. As peritoneal mesothelioma is more common in women, the prognosis and life expectancy are better. Male mesothelioma is more difficult to treat and has a lower survival rate than peritoneal mesothelioma, which is the most common form of the cancer among men.

There was a 2020 study published in the American Journal of Surgical Pathology that found that women with peritoneal cancer who received heated chemotherapy and cytoreductive surgery had a five-year survival rate of 77.8 percent, which is a significant improvement from previous findings. Approximately half of the men who have the procedure survive for that long with the disease on average.

As a whole, one's well-being and lifestyle choices

Life expectancy can be reduced if a person has other chronic conditions, like asbestosis or chronic bronchitis/emphysema (COPD), obesity, diabetes, or heart disease.

Tobacco use has been shown to reduce the chances of surviving mesothelioma. While smoking doesn't directly cause mesothelioma, people with the disease who smoke tend to have a shorter survival time after diagnosis.

Giving Patients a Better Quality of Life

Using anti-cancer therapies can extend life expectancy. With treatment, stage 4 mesothelioma patients can expect to live for about a year, compared to seven months without treatment.

"At first, you may feel completely alone if you've only just been diagnosed. This is a real shock. Don't give up. Follow the advice of your medical professionals and seek the care you require. It was clear to me from the beginning. "I had so much to look forward to,"

Chris Gibney

Mesothelioma of the lungs Survivor


  • Surgery
  • Chemotherapy
  • X-ray treatment
  • Immunotherapy
  • Clinical trials at TTFields

Early Intervention

Depending on their disease stage, patients with stage 1 or 2 cancer may be eligible for multimodal therapy, which includes surgery, chemotherapy, and radiation.

Patients with epithelial or biphasic cell types, who are younger and healthier, may also be eligible for combination treatments.

"Early Intervention."

Tumor Treating Fields therapy and immunotherapy are also options for late-stage treatment. Some people with late-stage mesothelioma may not be able to undergo surgery, but if your health is good enough, you may still be able to undergo this treatment method.

Patients with advanced mesothelioma who received pleurectomy and decortication surgery had a median survival time of nearly three years, according to a study published in 2017.

Clinical trials and new treatment options are discussed.

Participation in clinical trials testing new treatments is a common way for patients with mesothelioma to extend their life expectancy.

Using immunotherapy and photodynamic therapy, mesothelioma patients may be able to extend their lives. The use of gene therapy and other personalized treatments is currently under investigation.

Clinical trials tailored to your specific needs can be found by your oncologist.

Without treatment for mesothelioma, how long can you expect to live?

With no treatment, the average life expectancy for pleural mesothelioma is eight months.

In many cases, peritoneal mesothelioma responds more favorably to treatment than pleural cancer. With surgery and HIPEC (hyperthermic intraperitoneal chemotherapy), patients with peritoneal cancer can expect to live at least five years. However, without treatment, peritoneal mesothelioma cancer spreads rapidly. Peritoneal life expectancy without treatment is about six months on average. '

Many mesothelioma patients struggle with the decision of whether or not to seek treatment. Each person has the right to decide if the potential benefits of treatment outweigh the potential risks. Your loved ones can help you decide if treatment is right for you, and which treatments you are comfortable with, by discussing it with you first. There are no guarantees, but deciding to undergo treatment is your best hope of surviving mesothelioma for as long as possible.

Survival by Type of Mesothelioma and Treatment Decision





Pleural Mesothelioma

3 years

1 year

8 months

Peritoneal Mesothelioma

5 years

1 year

6 months


Based on a number of studies published in medical journals dating back decades.

With Mesothelioma, Increasing the Lifespan

Many people who have been diagnosed with mesothelioma have been able to live longer by taking active steps to improve their health, such as seeking specialized treatment and improving their nutrition.

Mesothelioma specialists can help you.

Many of the best cancer treatment and research facilities in the country employ mesothelioma doctors. Among these specialists are oncologists, surgeons, and others who offer the most advanced and promising treatment options for mesothelioma.

It is common for general oncologists to misdiagnose mesothelioma for other cancers or illnesses. It is possible to improve one's life expectancy with early and accurate mesothelioma diagnosis from a specialist, such as surgery.

Maintain a higher level of physical activity and fitness

It is a medical term that refers to a patient's level of physical activity and overall health. Almost all studies looking at the impact of performance status on survival in mesothelioma patients have found a connection.

Your body's ability to withstand and recover from aggressive cancer treatments is directly proportional to how physically active and fit you are.


Patients with cancer who receive better nutrition have a better prognosis. Eating a healthy diet can help your body recover from aggressive treatments and maintain a strong immune system, as well.

Diets for mesothelioma patients may have come up in conversation or in print. Ask your doctor for a recommendation to a cancer dietitian if you want to learn more about these diets.

When it comes to mesothelial cancer diets, adequate protein and calories are essential for a patient's recovery and for preventing weight loss.

Integrative Medicine

Conventional cancer treatment can be supplemented with other methods, such as complementary medicine. This method is referred to as "integrative medicine" or "integrative oncology." Acupuncture, meditation, herbal medicine, yoga, and support groups are just a few examples of alternative therapies. Stress and pain can be reduced by using these therapies.

Before beginning any integrative therapy, you should always consult your doctor to avoid drug interactions and negative treatment outcomes.


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